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CD47 Regulates Collagen I-Induced Cyclooxygenase-2 Expression and Intestinal Epithelial Cell Migration

Increased epithelial cell expression of the cyclooxgenase-2 (COX-2) enzyme is a characteristic event of both inflammatory bowel disease and colon cancer. We here report the novel findings that collagen I-induced de novo synthesis of COX-2 in intestinal epithelial cells is inhibited by pertussis toxi...

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Detalhes bibliográficos
Main Authors: Broom, Oliver Jay, Zhang, Yuan, Oldenborg, Per-Arne, Massoumi, Ramin, Sjölander, Anita
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2712095/
https://ncbi.nlm.nih.gov/pubmed/19636412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006371
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