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Degradation of Phosphorylated p53 by Viral Protein-ECS E3 Ligase Complex
p53-signaling is modulated by viruses to establish a host cellular environment advantageous for their propagation. The Epstein-Barr virus (EBV) lytic program induces phosphorylation of p53, which prevents interaction with MDM2. Here, we show that induction of EBV lytic program leads to degradation o...
Tallennettuna:
| Päätekijät: | , , , , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Public Library of Science
2009
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2712087/ https://ncbi.nlm.nih.gov/pubmed/19649319 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000530 |
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