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Pin-Hole Array Correlation Imaging: Highly Parallel Fluorescence Correlation Spectroscopy

In this work, we describe pin-hole array correlation imaging, a multipoint version of fluorescence correlation spectroscopy, based upon a stationary Nipkow disk and a high-speed electron multiplying charged coupled detector. We characterize the system and test its performance on a variety of samples...

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Detalhes bibliográficos
Main Authors: Needleman, Daniel J., Xu, Yangqing, Mitchison, Timothy J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2712041/
https://ncbi.nlm.nih.gov/pubmed/19527665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.03.023
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