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Identification of Inhibitors of ABCG2 by a Bioluminescence Imaging-based High-throughput Assay

ABCG2 is a member of the ATP-binding cassette (ABC) family of transporters, the overexpression of which is associated with tumor resistance to a variety of chemotherapeutic agents. Accordingly, combining ABCG2 inhibitor(s) with chemotherapy has the potential to improve treatment outcome. To search f...

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Detalhes bibliográficos
Main Authors: Zhang, Yimao, Byun, Youngjoo, Ren, Yunzhao R., Liu, Jun O., Laterra, John, Pomper, Martin G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711991/
https://ncbi.nlm.nih.gov/pubmed/19567678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-4866
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