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Soluble adenylyl cyclase-dependent microtubule disassembly reveals a novel mechanism of endothelial cell retraction

Soluble adenylyl cyclase toxins, such as Pseudomonas aeruginosa exoY, generate a cAMP pool that retracts cell borders. However, the cytoskeletal basis by which this cAMP signal retracts cell borders is not known. We sought to determine whether activation of chimeric, soluble adenylyl cyclase I/II (s...

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Bibliografske podrobnosti
Main Authors: Prasain, Nutan, Alexeyev, Mikhail, Balczon, Ron, Stevens, Troy
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711814/
https://ncbi.nlm.nih.gov/pubmed/19395666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.90577.2008
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