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Soluble adenylyl cyclase-dependent microtubule disassembly reveals a novel mechanism of endothelial cell retraction

Soluble adenylyl cyclase toxins, such as Pseudomonas aeruginosa exoY, generate a cAMP pool that retracts cell borders. However, the cytoskeletal basis by which this cAMP signal retracts cell borders is not known. We sought to determine whether activation of chimeric, soluble adenylyl cyclase I/II (s...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Prasain, Nutan, Alexeyev, Mikhail, Balczon, Ron, Stevens, Troy
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Physiological Society 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711814/
https://ncbi.nlm.nih.gov/pubmed/19395666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.90577.2008
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