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Soluble adenylyl cyclase-dependent microtubule disassembly reveals a novel mechanism of endothelial cell retraction

Soluble adenylyl cyclase toxins, such as Pseudomonas aeruginosa exoY, generate a cAMP pool that retracts cell borders. However, the cytoskeletal basis by which this cAMP signal retracts cell borders is not known. We sought to determine whether activation of chimeric, soluble adenylyl cyclase I/II (s...

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Detalhes bibliográficos
Main Authors: Prasain, Nutan, Alexeyev, Mikhail, Balczon, Ron, Stevens, Troy
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711814/
https://ncbi.nlm.nih.gov/pubmed/19395666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.90577.2008
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