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Knockdown of stromal interaction molecule 1 attenuates store-operated Ca(2+) entry and Ca(2+) responses to acute hypoxia in pulmonary arterial smooth muscle
Stromal interaction molecule 1 (STIM1) is a recently discovered membrane-spanning protein thought to sense lumenal Ca(2+) in sarco(endo)plasmic reticulum (SR/ER) and transduce activation of Ca(2+)-permeable store-operated channels (SOC) in plasmalemma in response to SR/ER Ca(2+) depletion. To evalua...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2711802/ https://ncbi.nlm.nih.gov/pubmed/19395668 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00063.2009 |
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