Carbon monoxide, skeletal muscle oxidative stress, and mitochondrial biogenesis in humans

Given that the physiology of heme oxygenase-1 (HO-1) encompasses mitochondrial biogenesis, we tested the hypothesis that the HO-1 product, carbon monoxide (CO), activates mitochondrial biogenesis in skeletal muscle and enhances maximal oxygen uptake (V̇o(2max)) in humans. In 10 healthy subjects, we...

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Main Authors: Rhodes, Michael A., Carraway, Martha Sue, Piantadosi, Claude A., Reynolds, Crystal M., Cherry, Anne D., Wester, T. E., Natoli, Michael J., Massey, E. Wayne, Moon, Richard E., Suliman, Hagir B.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711725/
https://ncbi.nlm.nih.gov/pubmed/19465554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00164.2009
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