Nitric oxide synthase-2 induction optimizes cardiac mitochondrial biogenesis after endotoxemia

Mitochondrial biogenesis protects metabolism from mitochondrial dysfunction produced by activation of innate immunity by lipopolysaccharide (LPS) or other bacterial products. Here we tested the hypothesis in mouse heart that activation of toll-like receptor-4 (TLR4), which induces early-phase genes...

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Bibliografiske detaljer
Main Authors: Reynolds, Crystal M., Suliman, Hagir B., Hollingsworth, John W., Welty-Wolf, Karen E., Carraway, Martha Sue, Piantadosi, Claude A.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666005/
https://ncbi.nlm.nih.gov/pubmed/19073249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2008.11.007
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