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Targeted disruption of the voltage-dependent calcium channel α(2)/δ-1-subunit
Cardiac L-type voltage-dependent Ca(2+) channels are heteromultimeric polypeptide complexes of α(1)-, α(2)/δ-, and β-subunits. The α(2)/δ-1-subunit possesses a stereoselective, high-affinity binding site for gabapentin, widely used to treat epilepsy and postherpetic neuralgic pain as well as sleep d...
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Principais autores: | , , , , , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Physiological Society
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2711723/ https://ncbi.nlm.nih.gov/pubmed/19429829 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00122.2009 |
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