Pressure activates epidermal growth factor receptor leading to the induction of iNOS via NFκB and STAT3 in human proximal tubule cells

Ureteral obstruction leads to increased pressure and inducible nitric oxide synthase (iNOS) expression. This study examined the involvement of epidermal growth factor (EGF) receptor (EGFR), nuclear factor-κB (NFκB), and signal transducers and activators of transcription 3 (STAT3) in iNOS induction i...

Full description

Saved in:
Bibliographic Details
Main Authors: Broadbelt, Nalini V., Chen, Jie, Silver, Randi B., Poppas, Dix P., Felsen, Diane
Format: Artigo
Language:Inglês
Published: American Physiological Society 2009
Subjects:
Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711717/
https://ncbi.nlm.nih.gov/pubmed/19403642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.90752.2008
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items