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Pressure activates epidermal growth factor receptor leading to the induction of iNOS via NFκB and STAT3 in human proximal tubule cells

Ureteral obstruction leads to increased pressure and inducible nitric oxide synthase (iNOS) expression. This study examined the involvement of epidermal growth factor (EGF) receptor (EGFR), nuclear factor-κB (NFκB), and signal transducers and activators of transcription 3 (STAT3) in iNOS induction i...

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Bibliografiske detaljer
Main Authors: Broadbelt, Nalini V., Chen, Jie, Silver, Randi B., Poppas, Dix P., Felsen, Diane
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711717/
https://ncbi.nlm.nih.gov/pubmed/19403642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.90752.2008
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