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β1-Integrin is required for kidney collecting duct morphogenesis and maintenance of renal function
Deletion of integrin-β1 (Itgb1) in the kidney collecting system led to progressive renal dysfunction and polyuria. The defect in the concentrating ability of the kidney was concomitant with decreased medullary collecting duct expression of aquaporin-2 and arginine vasopressin receptor 2, while histo...
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| Autors principals: | , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Physiological Society
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2711709/ https://ncbi.nlm.nih.gov/pubmed/19439520 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.90260.2008 |
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