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β1-Integrin is required for kidney collecting duct morphogenesis and maintenance of renal function

Deletion of integrin-β1 (Itgb1) in the kidney collecting system led to progressive renal dysfunction and polyuria. The defect in the concentrating ability of the kidney was concomitant with decreased medullary collecting duct expression of aquaporin-2 and arginine vasopressin receptor 2, while histo...

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Detaylı Bibliyografya
Asıl Yazarlar: Wu, Wei, Kitamura, Shinji, Truong, David M., Rieg, Timo, Vallon, Volker, Sakurai, Hiroyuki, Bush, Kevin T., Vera, David R., Ross, Robert S., Nigam, Sanjay K.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711709/
https://ncbi.nlm.nih.gov/pubmed/19439520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.90260.2008
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