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Hyperphagia and obesity produced by arcuate injection of NPY–saporin do not require upregulation of lateral hypothalamic orexigenic peptide genes

Neuropeptide Y (NPY) conjugated with a ribosomal inactivating toxin, saporin (SAP), is a toxin that targets NPY receptor-expressing cells. Injection of NPY–SAP into the rat arcuate nucleus (Arc) and basomedial hypothalamus (BMH) destroys two populations of NPY-receptor-expressing neurons important f...

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Hlavní autoři: Li, Ai-Jun, Dinh, Thu T., Ritter, Sue
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711633/
https://ncbi.nlm.nih.gov/pubmed/18577407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.peptides.2008.05.026
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