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Hypothalamic tanycytes generate acute hyperphagia through activation of the arcuate neuronal network

Hypothalamic tanycytes are chemosensitive glial cells that contact the cerebrospinal fluid in the third ventricle and send processes into the hypothalamic parenchyma. To test whether they can activate neurons of the arcuate nucleus, we targeted expression of a Ca(2+)-permeable channelrhodopsin (CatC...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Bolborea, Matei, Pollatzek, Eric, Benford, Heather, Sotelo-Hitschfeld, Tamara, Dale, Nicholas
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7322081/
https://ncbi.nlm.nih.gov/pubmed/32513737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1919887117
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