Decorin is a novel antagonistic ligand of the Met receptor

Decorin, a member of the small leucine-rich proteoglycan gene family, impedes tumor cell growth by down-regulating the epidermal growth factor receptor. Decorin has a complex binding repertoire, thus, we predicted that decorin would modulate the bioactivity of other tyrosine kinase receptors. We dis...

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Bibliografiske detaljer
Main Authors: Goldoni, Silvia, Humphries, Ashley, Nyström, Alexander, Sattar, Sampurna, Owens, Rick T., McQuillan, David J., Ireton, Keith, Iozzo, Renato V.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2009
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711571/
https://ncbi.nlm.nih.gov/pubmed/19433454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200901129
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