Adenovirus vector-induced immune responses in nonhuman primates: responses to prime boost regimens

In the phase IIb STEP trial an HIV-1 vaccine based on adenovirus (Ad) vectors of the human serotype 5 (AdHu5) not only failed to induce protection but also increased susceptibility to HIV-1 infection in individuals with pre-existing neutralizing antibodies against AdHu5. The mechanisms underlying th...

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מידע ביבליוגרפי
Main Authors: Tatsis, Nia, Lasaro, Marcio O., Lin, Shih-Wen, Xiang, Zhi Q., Zhou, Dongming, DiMenna, Lauren, Li, Hua, Bian, Ang, Abdulla, Sarah, Li, Yan, Giles-Davis, Wynetta, Engram, Jessica, Ratcliffe, Sarah J., Silvestri, Guido, Ertl, Hildegund C., Betts, Michael R.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2009
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711537/
https://ncbi.nlm.nih.gov/pubmed/19414814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900317
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