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Purifying selection and birth-and-death evolution in the ubiquitin gene family

Ubiquitin is a highly conserved protein that is encoded by a multigene family. It is generally believed that this gene family is subject to concerted evolution, which homogenizes the member genes of the family. However, protein homogeneity can be attained also by strong purifying selection. We there...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Nei, Masatoshi, Rogozin, Igor B., Piontkivska, Helen
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2000
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC27115/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11005860/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.20.10866
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