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Transmembrane Helix Association Affinity Can Be Modulated by Flanking and Noninterfacial Residues

The GxxxG sequence motif mediates the association of transmembrane (TM) helices by providing a site of close contact between them. However, it is not sufficient for strong association. For example, both bacteriophage M13 major coat protein (MCP) and human erythrocyte protein glycophorin A (GpA) cont...

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書目詳細資料
Main Authors: Zhang, Jinming, Lazaridis, Themis
格式: Artigo
語言:Inglês
出版: The Biophysical Society 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711494/
https://ncbi.nlm.nih.gov/pubmed/19486666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.03.008
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