Effect of B7.1 Costimulation on T-Cell Based Immunity against TAP-Negative Cancer Can Be Facilitated by TAP1 Expression

Tumors deficient in expression of the transporter associated with antigen processing (TAP) usually fail to induce T-cell-mediated immunity and are resistant to T-cell lysis. However, we have found that introduction of the B7.1 gene into TAP-negative (TAP(−)) or TAP1-transfected (TAP1(+)) murine lung...

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Main Authors: Li, Xiao-Lin, Liu, Yong-Yu, Knight, David, Odaka, Yoshinobu, Mathis, J. Michael, Shi, Runhua, Glass, Jonathan, Zhang, Qian-Jin
格式: Artigo
語言:Inglês
出版: Public Library of Science 2009
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711302/
https://ncbi.nlm.nih.gov/pubmed/19629186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006385
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