The novel RASSF6 and RASSF10 candidate tumour suppressor genes are frequently epigenetically inactivated in childhood leukaemias

BACKGROUND: The Ras-assocation family (RASSF) of tumour suppressor genes (TSGs) contains 10 members that encode proteins containing Ras-assocation (RA) domains. Several members of the RASSF family are frequently epigenetically inactivated in cancer, however, their role in leukaemia has remained larg...

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Main Authors: Hesson, Luke B, Dunwell, Thomas L, Cooper, Wendy N, Catchpoole, Daniel, Brini, Anna T, Chiaramonte, Raffaella, Griffiths, Mike, Chalmers, Andrew D, Maher, Eamonn R, Latif, Farida
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2009
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711046/
https://ncbi.nlm.nih.gov/pubmed/19570220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-8-42
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