Frequent epigenetic inactivation of KIBRA, an upstream member of the Salvador/Warts/Hippo (SWH) tumor suppressor network, is associated with specific genetic event in B-cell acute lymphocytic leukemia

The WW-domain containing protein KIBRA has recently been identified as a new member of the Salvador/Warts/Hippo (SWH) pathway in Drosophila and is shown to act as a tumor suppressor gene in Drosophila. This pathway is conserved in humans and members of the pathway have been shown to act as tumor sup...

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Detalhes bibliográficos
Main Authors: Hill, Victoria K, Dunwell, Thomas, Catchpoole, Daniel, Krex, Dietmar, Brini, Anna T, Griffiths, Mike, Craddock, Charles, Maher, Eamonn R, Latif, Farida
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3092681/
https://ncbi.nlm.nih.gov/pubmed/21173572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.6.3.14404
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