Evidence for a mitochondrial localization of the retinoblastoma protein

BACKGROUND: The retinoblastoma protein (Rb) plays a central role in the regulation of cell cycle, differentiation and apoptosis. In cancer cells, ablation of Rb function or its pathway is a consequence of genetic inactivation, viral oncoprotein binding or deregulated hyperphosphorylation. Some recen...

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Main Authors: Ferecatu, Ioana, Le Floch, Nathalie, Bergeaud, Marie, Rodríguez-Enfedaque, Aida, Rincheval, Vincent, Oliver, Lisa, Vallette, François M, Mignotte, Bernard, Vayssière, Jean-Luc
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2009
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711044/
https://ncbi.nlm.nih.gov/pubmed/19555499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-10-50
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