The Human Promyelocytic Leukemia Protein is a Tumor Suppressor for Murine Skin Carcinogenesis

Expression of the PMLRARα fusion dominant-negative oncogene in the epidermis of transgenic mice resulted in spontaneous skin tumors attributed to changes in both the PML and RAR pathways [1]. To determine the contribution of PML to skin tumor susceptibility, transgenic mice were generated on an FVB/...

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Détails bibliographiques
Auteurs principaux: Virador, Victoria M., Flores-Obando, Rafael E., Berry, Adam, Patel, Rinal, Zakhari, Julia, Lo, Yu-Chien, Strain, Kathryn, Anders, Joanna, Cataisson, Christophe, Hansen, Laura A., Yuspa, Stuart H.
Format: Artigo
Langue:Inglês
Publié: 2009
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711034/
https://ncbi.nlm.nih.gov/pubmed/19058256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.20498
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