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Keratinocyte p38δ loss inhibits Ras-induced tumor formation, while systemic p38δ loss enhances skin inflammation in the early phase of chemical carcinogenesis in mouse skin

p38δ expression and/or activity are increased in human cutaneous malignancies, including invasive squamous cell carcinoma (SCC) and head and neck SCC, but the role of p38δ in cutaneous carcinogenesis has not been well-defined. We have reported that mice with germline loss of p38δ exhibited a reduced...

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Bibliografski detalji
Izdano u:Mol Carcinog
Glavni autori: Kiss, Alexi, Koppel, Aaron C., Anders, Joanna, Cataisson, Christophe, Yuspa, Stuart H., Blumenberg, Miroslav, Efimova, Tatiana
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6310148/
https://ncbi.nlm.nih.gov/pubmed/25753147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22303
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