Expression of Scl in mesoderm rescues hematopoiesis in the absence of Oct-4

In embryonic stem cells, Oct-4 concentration is critical in determining the development of endoderm, mesoderm, and trophectoderm. Although Oct-4 expression is essential for mesoderm development, it is unclear whether it has a role in the development of specific mesodermal tissues. In this study, we...

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Bibliographic Details
Main Authors: Kong, Kimi Y., Williamson, Elizabeth A., Rogers, Jason H., Tran, Tam, Hromas, Robert, Dahl, Richard
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2009
Subjects:
Hematopoiesis and Stem Cells
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2710954/
https://ncbi.nlm.nih.gov/pubmed/19321862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-08-174755
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