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Level of major histocompatibility complex class I expression on endothelium in non-obese diabetic mice influences CD8 T cell adhesion and migration

An important prerequisite for development of insulitis and β-cell destruction in type 1 diabetes is successful transmigration of autoreactive T cells across the islet endothelium. Previous work suggests that antigen presentation to T cells by endothelium, which requires endothelial cell expression o...

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Detalhes bibliográficos
Main Authors: Lozanoska-Ochser, B, Peakman, M
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2710599/
https://ncbi.nlm.nih.gov/pubmed/19659777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2009.03940.x
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