Immunomodulatory drug FTY720 induces regulatory CD4(+)CD25(+) T cells in vitro

As a novel immunosuppressant, FTY720 (2-amino-2-(2-[4-octylphenyl] ethyl)-1, 3-propanediol hydrochloride) has been used to prevent the allograft rejection in organ transplantation. FTY720 can prolong markedly survival of the allograft by inducing apoptosis of reactive lymphocytes and by redirecting...

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Bibliografiske detaljer
Main Authors: Zhou, P J, Wang, H, Shi, G H, Wang, X H, Shen, Z J, Xu, D
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2009
Fag:
Translational Studies
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2710591/
https://ncbi.nlm.nih.gov/pubmed/19659769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2009.03942.x
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