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Immunomodulatory drug FTY720 induces regulatory CD4(+)CD25(+) T cells in vitro
As a novel immunosuppressant, FTY720 (2-amino-2-(2-[4-octylphenyl] ethyl)-1, 3-propanediol hydrochloride) has been used to prevent the allograft rejection in organ transplantation. FTY720 can prolong markedly survival of the allograft by inducing apoptosis of reactive lymphocytes and by redirecting...
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Main Authors: | , , , , , |
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Format: | Artigo |
Jezik: | Inglês |
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Blackwell Science Inc
2009
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2710591/ https://ncbi.nlm.nih.gov/pubmed/19659769 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2009.03942.x |
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