The NALCN ion channel is activated by M3 muscarinic receptors in a pancreatic β-cell line

A previously uncharacterized putative ion channel, NALCN (sodium leak channel, non-selective), has been recently shown to be responsible for the tetrodotoxin (TTX)-resistant sodium leak current implicated in the regulation of neuronal excitability. Here, we show that NALCN encodes a current that is...

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Hlavní autoři: Swayne, Leigh Anne, Mezghrani, Alexandre, Varrault, Annie, Chemin, Jean, Bertrand, Gyslaine, Dalle, Stephane, Bourinet, Emmanuel, Lory, Philippe, Miller, Richard J, Nargeot, Joel, Monteil, Arnaud
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2009
Témata:
Scientific Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2710536/
https://ncbi.nlm.nih.gov/pubmed/19575010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2009.125
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