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Calcium Dysregulation Induces Apoptosis-inducing Factor Release: Cross-talk Between PARP-1- and Calpain- Signaling Pathways

Recent discoveries show that caspase-independent cell death pathways are a pervasive mechanism in neurodegenerative diseases, and apoptosis-inducing factor (AIF) is an important effector of this mode of neuronal death. There are currently two known mechanisms underlying AIF release following excitot...

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Detalhes bibliográficos
Main Authors: Vosler, Peter S., Sun, Dandan, Wang, Suping, Gao, Yanqin, Kintner, Douglas B., Signore, Armando P., Cao, Guodong, Chen, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2710414/
https://ncbi.nlm.nih.gov/pubmed/19427306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2009.04.032
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