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Brain-derived neurotrophic factor regulates energy balance downstream of melanocortin-4 receptor
The melanocortin-4 receptor (MC4R) is critically involved in regulating energy balance, and obesity has been observed in mice with mutations in the gene for brain-derived neurotrophic factor (BDNF). Here we report that BDNF is expressed at high levels in the ventromedial hypothalamus (VMH) where its...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2003
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2710100/ https://ncbi.nlm.nih.gov/pubmed/12796784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn1073 |
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