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Brain-derived neurotrophic factor regulates energy balance downstream of melanocortin-4 receptor

The melanocortin-4 receptor (MC4R) is critically involved in regulating energy balance, and obesity has been observed in mice with mutations in the gene for brain-derived neurotrophic factor (BDNF). Here we report that BDNF is expressed at high levels in the ventromedial hypothalamus (VMH) where its...

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Detalhes bibliográficos
Main Authors: Xu, Baoji, Goulding, Evan H, Zang, Keling, Cepoi, David, Cone, Roger D, Jones, Kevin R, Tecott, Laurence H, Reichardt, Louis F
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2710100/
https://ncbi.nlm.nih.gov/pubmed/12796784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn1073
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