Induced Secondary Structure and Polymorphism in an Intrinsically Disordered Structural Linker of the CNS: Solid-State NMR and FTIR Spectroscopy of Myelin Basic Protein Bound to Actin

The 18.5 kDa isoform of myelin basic protein (MBP) is a peripheral membrane protein that maintains the structural integrity of the myelin sheath of the central nervous system by conjoining the cytoplasmic leaflets of oligodendrocytes and by linking the myelin membrane to the underlying cytoskeleton...

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Detalhes bibliográficos
Main Authors: Ahmed, Mumdooh A.M., Bamm, Vladimir V., Shi, Lichi, Steiner-Mosonyi, Marta, Dawson, John F., Brown, Leonid, Harauz, George, Ladizhansky, Vladimir
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2009
Assuntos:
Protein
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2710047/
https://ncbi.nlm.nih.gov/pubmed/19134474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2008.10.003
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