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Monitoring of an RNA Multistep Folding Pathway by Isothermal Titration Calorimetry
Isothermal titration calorimetry was used to monitor the energetic landscape of a catalytic RNA, specifically that of the hepatitis delta virus ribozyme. Using mutants that isolated various tertiary interactions, the thermodynamic parameters of several ribozyme-substrate intermediates were determine...
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| Main Authors: | , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
The Biophysical Society
2009
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2710038/ https://ncbi.nlm.nih.gov/pubmed/19134473 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2008.09.033 |
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