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LFA-1 Binding Destabilizes the JAM-A Homophilic Interaction During Leukocyte Transmigration

Leukocyte transendothelial migration into inflamed areas is regulated by the integrity of endothelial cell junctions and is stabilized by adhesion molecules including junctional adhesion molecule-A (JAM-A). JAM-A has been shown to participate in homophilic interactions with itself and in heterophili...

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Detalhes bibliográficos
Main Authors: Wojcikiewicz, Ewa P., Koenen, Rory R., Fraemohs, Line, Minkiewicz, Julia, Azad, Hashem, Weber, Christian, Moy, Vincent T.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2710021/
https://ncbi.nlm.nih.gov/pubmed/18849408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.135491
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