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Hypocretin-2 Saporin Lesions of the Ventrolateral Periaquaductal Gray (vlPAG) Increase REM Sleep in Hypocretin Knockout Mice

Ten years ago the sleep disorder narcolepsy was linked to the neuropeptide hypocretin (HCRT), also known as orexin. This disorder is characterized by excessive day time sleepiness, inappropriate triggering of rapid-eye movement (REM) sleep and cataplexy, which is a sudden loss of muscle tone during...

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Библиографические подробности
Главные авторы: Kaur, Satvinder, Thankachan, Stephen, Begum, Suraiya, Liu, Meng, Blanco-Centurion, Carlos, Shiromani, Priyattam J.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709920/
https://ncbi.nlm.nih.gov/pubmed/19623260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006346
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