Selective Degeneration of Central Photoreceptors after Hyperbaric Oxygen in Normal and Metallothionein-Knockout Mice

PURPOSE: Metallothioneins (MTs) in the brain and retina are believed to bind metals and reduce free radicals, thereby protecting neurons from oxidative damage. This study was undertaken to investigate whether retinal photoreceptor (PR) cells lacking MTs are more susceptible to hyperbaric oxygen (HBO...

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Main Authors: Nachman-Clewner, Michele, Giblin, Frank J., Kathleen Dorey, C., Blanks, Robert H. I., Dang, Loan, Dougherty, Christopher J., Blanks, Janet C.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709831/
https://ncbi.nlm.nih.gov/pubmed/18579766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.07-1039
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