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Redefining the p53 response element

The tumor suppressor p53 is a master transcriptional regulator that affects a diverse range of cellular events. Surprisingly, even with >100 validated p53 response element (RE) sequences available, the effect of p53 binding on transcriptional behavior is seldom predictable and no functional rules...

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Autori principali: Wang, Bei, Xiao, Ziwei, Ren, Ee Chee
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709670/
https://ncbi.nlm.nih.gov/pubmed/19597154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0903284106
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