MLL rearrangements in pediatric acute lymphoblastic and myeloblastic leukemias: MLL specific and lineage specific signatures

BACKGROUND: The presence of MLL rearrangements in acute leukemia results in a complex number of biological modifications that still remain largely unexplained. Armstrong et al. proposed MLL rearrangement positive ALL as a distinct subgroup, separated from acute lymphoblastic (ALL) and myeloblastic l...

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Hlavní autoři: Zangrando, Andrea, Dell'Orto, Marta Campo, te Kronnie, Geertruy, Basso, Giuseppe
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2009
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709660/
https://ncbi.nlm.nih.gov/pubmed/19549311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-2-36
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