A functional polymorphism in the SPINK5 gene is associated with asthma in a Chinese Han Population

BACKGROUND: Mutation in SPINK5 causes Netherton syndrome, a rare recessive skin disease that is accompanied by severe atopic manifestations including atopic dermatitis, allergic rhinitis, asthma, high serum IgE and hypereosinophilia. Recently, single nucleotide polymorphism (SNP) of the SPINK5 was s...

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Bibliografiske detaljer
Main Authors: Liu, Qiji, Xia, Yu, Zhang, Wenjing, Li, Jisheng, Wang, Pin, Li, Huaichen, Wei, Chunhua, Gong, Yaoqin
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2009
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709655/
https://ncbi.nlm.nih.gov/pubmed/19534795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-10-59
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