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A functional polymorphism in the SPINK5 gene is associated with asthma in a Chinese Han Population

BACKGROUND: Mutation in SPINK5 causes Netherton syndrome, a rare recessive skin disease that is accompanied by severe atopic manifestations including atopic dermatitis, allergic rhinitis, asthma, high serum IgE and hypereosinophilia. Recently, single nucleotide polymorphism (SNP) of the SPINK5 was s...

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Detalhes bibliográficos
Main Authors: Liu, Qiji, Xia, Yu, Zhang, Wenjing, Li, Jisheng, Wang, Pin, Li, Huaichen, Wei, Chunhua, Gong, Yaoqin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709655/
https://ncbi.nlm.nih.gov/pubmed/19534795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-10-59
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