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Both helix topology and counterion distribution contribute to the more effective charge screening in dsRNA compared with dsDNA

The recent discovery of the RNA interference mechanism emphasizes the biological importance of short, isolated, double-stranded (ds) RNA helices and calls for a complete understanding of the biophysical properties of dsRNA. However, most previous studies of the electrostatics of nucleic acid duplexe...

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Detalhes bibliográficos
Main Authors: Pabit, Suzette A., Qiu, Xiangyun, Lamb, Jessica S., Li, Li, Meisburger, Steve P., Pollack, Lois
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709557/
https://ncbi.nlm.nih.gov/pubmed/19395592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp257
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