Both helix topology and counterion distribution contribute to the more effective charge screening in dsRNA compared with dsDNA

The recent discovery of the RNA interference mechanism emphasizes the biological importance of short, isolated, double-stranded (ds) RNA helices and calls for a complete understanding of the biophysical properties of dsRNA. However, most previous studies of the electrostatics of nucleic acid duplexe...

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Bibliografiske detaljer
Main Authors: Pabit, Suzette A., Qiu, Xiangyun, Lamb, Jessica S., Li, Li, Meisburger, Steve P., Pollack, Lois
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2009
Fag:
RNA
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709557/
https://ncbi.nlm.nih.gov/pubmed/19395592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp257
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