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Agonist-dependent phosphorylation of the formyl peptide receptor is regulated by the membrane proximal region of the cytoplasmic tail

Formyl peptide receptor (FPR) is a chemoattractant G protein-coupled receptor (GPCR) involved in the innate immune response against bacteria. Receptor activation is terminated by receptor phosphorylation of two serine- and threonine-rich regions located in the distal half of the cytoplasmic tail. In...

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Библиографические подробности
Главные авторы: Suvorova, Elena S., Gripentrog, Jeannie M., Jesaitis, Algirdas J., Miettinen, Heini M.
Формат: Artigo
Язык:Inglês
Опубликовано: 2008
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709459/
https://ncbi.nlm.nih.gov/pubmed/18952127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2008.09.011
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