A phosphatase activity of Sts-1 contributes to the suppression TCR signaling

Precise signaling by the T cell receptor (TCR) is crucial for a proper immune response. To ensure that T cells respond appropriately to antigenic stimuli, TCR signaling pathways are subject to multiple levels of regulation. Sts-1 negatively regulates signaling pathways downstream of the TCR by an un...

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Bibliographische Detailangaben
Hauptverfasser: Mikhailik, Anatoly, Ford, Bradley, Keller, James, Chen, Yunting, Nassar, Nicolas, Carpino, Nick
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709417/
https://ncbi.nlm.nih.gov/pubmed/17679096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.06.015
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