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A phosphatase activity of Sts-1 contributes to the suppression TCR signaling
Precise signaling by the T cell receptor (TCR) is crucial for a proper immune response. To ensure that T cells respond appropriately to antigenic stimuli, TCR signaling pathways are subject to multiple levels of regulation. Sts-1 negatively regulates signaling pathways downstream of the TCR by an un...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2709417/ https://ncbi.nlm.nih.gov/pubmed/17679096 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.06.015 |
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