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Specificity of Binding of the Low Density Lipoprotein Receptor-related Protein to Different Conformational States of the Clade E Serpins Plasminogen Activator Inhibitor-1 and Proteinase Nexin-1
The low density lipoprotein receptor-related protein (LRP) is the principal clearance receptor for serpins and serpin-proteinase complexes. The ligand binding regions of LRP consist of clusters of cysteine-rich ∼40-residue complement-like repeats (CR), with cluster II being the principal ligand-bind...
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Hauptverfasser: | , , |
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Format: | Artigo |
Sprache: | Inglês |
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American Society for Biochemistry and Molecular Biology
2009
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Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2709341/ https://ncbi.nlm.nih.gov/pubmed/19439404 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.009530 |
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