Specificity of Binding of the Low Density Lipoprotein Receptor-related Protein to Different Conformational States of the Clade E Serpins Plasminogen Activator Inhibitor-1 and Proteinase Nexin-1

The low density lipoprotein receptor-related protein (LRP) is the principal clearance receptor for serpins and serpin-proteinase complexes. The ligand binding regions of LRP consist of clusters of cysteine-rich ∼40-residue complement-like repeats (CR), with cluster II being the principal ligand-bind...

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Detalles Bibliográficos
Main Authors: Jensen, Jan K., Dolmer, Klavs, Gettins, Peter G. W.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Protein Structure and Folding
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709341/
https://ncbi.nlm.nih.gov/pubmed/19439404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.009530
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