Promoter Polymorphisms in ACE (Angiotensin I–Converting Enzyme) Associated With Clinical Outcomes in Hypertension

Genetic variants of ACE are suspected risk factors in cardiovascular disease, but the alleles responsible for the variations remain unidentified. To search for regulatory polymorphisms, allelic angiotensin I–converting enzyme (ACE) mRNA expression was measured in 65 heart tissues, followed by genoty...

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Bibliographic Details
Main Authors:	Johnson, AD, Gong, Y, Wang, D, Langaee, TY, Shin, J, Cooper-DeHoff, RM, Schork, NJ, Binkley, P, Pepine, CJ, Johnson, JA, Sadee, W
Format:	Artigo
Language:	Inglês
Published:	2008
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2709290/ https://ncbi.nlm.nih.gov/pubmed/18946466 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/clpt.2008.194
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Promoter Polymorphisms in ACE (Angiotensin I–Converting Enzyme) Associated With Clinical Outcomes in Hypertension

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